dehydroepiandrosterone

Dehydroepiandrosterone Structural Formula

Structural formula

Business number	0160
Molecular formula	C19H28O2
Molecular weight	288.42
label	dehydroepiandrosterone, Dehydroepiandrosterone, (3β)-3-Hydroxy-5-en-17-sterone, 3β-hydroxy-5-androsten-17-one, trans-dehydroepiandrosterone, Dehydroepiandrosterone, dehydroepiandrosterone, Androgen-5-en-3B-ol-17one, prasterone, trans-Dehydroandrosterone

Numbering system

CAS number:53-43-0

MDL number:MFCD00003613

EINECS number:200-175-5

RTECS number:BV8396000

BRN number:2058110

PubChem number:24278369

Physical property data

1. Character: White needles or sheets crystal-like.

2. Density (g/mL,25/4): Undetermined

3. Relative vapor density (g/mL,AIR=1): Undetermined

4. Melting point (ºC): 140~141℃(needle-shaped),152～153(flake)

5. Boiling point (ºC,Normal pressure): Undetermined

6. Boiling point (ºC,5.2kPa): Undetermined

7. Refractive index: undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º): [α]_D¹⁸+10.9°（ C=0.4, in ethanol)

10.Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturated vapor pressure (kPa,60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil and water (octanol/Log value of partition coefficient (water): undetermined

17. Explosion limit (%,V/V): Undetermined

18. Lower explosion limit (%,V/V): Undetermined

19. Solubility:Soluble in benzene, ethanol and ether, slightly soluble in chloroform and petroleum ether. Can be precipitated by digitonin

Toxicological data

None yet

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 83.11

2. Molar volume (m³/mol）：256.9

3. isotonic ratio(90.2K)：663.6

4. Surface Tension(dyne/cm)：44.4

5. Polarizability(10-24cm³)：32.94

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: 2

6. Topological molecule polar surface area 37.3

7. Number of heavy atoms: 21

8. Surface charge: 0

9. Complexity: 508

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 6

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and Stability

None yet

Storage method

Seal and store in a cool place away from light.

Synthesis method

3β-Hydroxy-5-Androsten -17- Ketone, also known as dehydroepiandrosterone, abbreviationDHAor DHEA. It has a weak androgenic effect and can be detected in urine, often excreted in the form of sulfate ester.

Purpose

DHEA（dehydrpepiandrosterone) is the precursor of androstenedione, testosterone and other male hormones, and can increase the levels of male hormones. DHEAIt is the most abundant hormone in the human body, thousands of times more than other hormones in the body. It is produced by the adrenal glands and is also known as“Anti-aging hormone” . Research shows:DHEACan regulate and promote other substances in the body18The secretion of steroid hormones in the body has the functions of promoting metabolism, maintaining normal functions of the human body, anti-aging and enhancing immunity, so it is also called“Youth Factor“. Clinical research,DHEACan improve immune function, resist degeneration and prevent infectious diseases, and can promote the immune systemtCell,bProduction of cells and macrophages, preventing bacterial and viral infections, inhibiting obesity and preventing cancer , lower cholesterol and blood lipids